Prof. Dr. med. Dorothee Mielke 

Oberärztinnen /-ärzte  -  Leitende Oberärztin

Robert-Koch-Straße 40
37075 Göttingen
0551 3966033
0551 398794
E-Mail

 
 

Aus- und Weiterbildung

Studium:

1998 - 2003, Charité Berlin, Campus Benjamin Franklin 
2003 - 2004, Ruprecht-Karls-Universität Heidelberg, Klinik Mannheim

Approbation:
01.10.2004

Promotion:
23.06.2006; Thema: "Funktionelle Neuronavigation" - Korrelation von präoperativen fMRT- Daten mit dem navigationsunterstützten intraoperativen neurophysiologischen Monitoring

Ausbildung:
11/2004-03/2005, Abteilung für Unfall-, Rekonstruktive und Plastische Chirurgie, Universitätsklinikum Leipzig, 04/2005-08/2008; Abteilung für Neurochirurgie, Universitätsklinikum Giessen und Marburg GmbH, Standort Giessen

Facharztanerkennung: 13.12.2010

Habilitation:

14.11.2011; Thema: Aneurysmatische Subarachnoidalblutung - Neue Aspekte der Diagnostik und Therapie

Schwerpunkte

Klinische Schwerpunkte: 

Vaskuläre Neurochirurgie, adjuvante Hirntumortherapie

Wissenschaftliche Schwerpunkte: 

Elektrische Beeinflussung der Hirndurchblutung, Vasospasmus nach SAB

Publikationen

Schläger C, Körner H, Krueger M, Vidoli S, Haberl M, Mielke D, Brylla E, Issekutz T, Cabañas C, Nelson PJ, Ziemssen T, Rohde V, Bechmann I, Lodygin D, Odoardi F, Flügel A. Effector T-cell trafficking between the leptomeninges and the cerebrospinal fluid. Nature 530:349-353, 2016

Malinova V, Schatlo B, Voit M, Suntheim P, Rohde V, Mielke D. Identification of specific age groups with a high risk for developing cerebral vasospasm after aneurysmal subarachnoid hemorrhage. Neurosurg Rev 39:429-436, 2016

Malinova V, Dolatowski K, Schramm P, Moerer O, Rohde V, Mielke D. Early whole-brain CT perfusion for detection of patients at risk for delayed cerebral ischemia after subarachnoid hemorrhage. J Neurosurg. 2015 Dec 18:1-9. [Epub ahead of print]

Mielke D, Kallenberg K, Hartmann M, Rohde V. Paraplegia after contrast media application: a transient or devastating rare complication? Case report. J Neurosurg Spine. 2015 Nov 6:1-4. [Epub aheadof print]

Giese H, Sauvigny T, Sakowitz OW, Bierschneider M, Güresir E, Henker C, Höhne J, Lindner D, Mielke D, Pannewitz R, Rohde V, Scholz M, Schuss P, Regelsberger J. German Cranial Reconstruction Registry (GCRR): protocol for a prospective, multicentre, open registry. BMJ Open. 2015 Sep 30

Wostrack M, Mielke D, Kato N, Guhl S, Schmidt NO, Maldaner N, Vajkoczy P, Dengler J; Giant Intracranial Aneurysm Study Group. Interobserver variability in the characterization of giant intracranial aneurysms with special emphasis on aneurysm diameter and shape. Acta Neurochir (Wien) 157(11):1859-65, 2015.

Mielke D, Rohde V. Bilateral spinal canal decompression via hemilaminectomy in cervical spondylotic myelopathy. Acta Neurochir (Wien) 157(10):1813-7, 2015.

Malinova V, von Eckardstein K, Rohde V, Mielke D. Neuronavigated microvascular Doppler sonography for intraoperative monitoring of blood flow velocity changes during aneurysm surgery - A feasible monitoring technique. Clin Neurol Neurosurg 2(137):79-82, 2015.

Maldaner N, Guhl S, Mielke D, Musahl C, Schmidt NO, Wostrack M, Rüfenacht DA, Vajkoczy P, Dengler J; Giant Intracranial Aneurysm Study Group. Changes in volume of giant intracranial aneurysms treated by surgical strategies other than direct clipping. Acta Neurochir (Wien) 157(7):1117-23, 2015.

Dengler J, Maldaner N, Bijlenga P, Burkhardt J-K, Hong B, Hohaus C, Graewe A, Guhl S, Kursumovic A, Mielke D, Schebesch K-M, Wostrack M, Rufenacht D, Vajkoczy P, Schmidt NO. For the Giant Intracranial Aneurysm Study Group. Perianeurysmal edema in giant intracranial aneurysms in relation to aneurysm location, size and partial thrombosis. J Neurosurg 123(2):446-52, 2015.

Zafar N, Alaid A, Rohde V, Mielke D. Intermittent visual field defects caused by a dilated Virchow-Robin space close to the optic radiation: Therapeutic and pathomechanical considerations. Br J Neurosurg 29(4):549-51, 2015.

Dengler J, Maldaner N, Bijlenga P, Burkhardt J-K, Graewe A, Guhl S, Nakamura M, Hohaus C, Kursumovic A, Schmidt NO, Schebesch K-M, Wostrack M, Vajkoczy P, Mielke D On behalf of the Giant Intracranial Aneurysm Study Group. Quantifying unruptured giant intracranial aneurysms by measuring diameter and volume - a comparative analysis of 69 cases. Acta Neurochir (Wien) 157:361-368, 2015.

Rohde V, Mielke D, Ryang Y, Gilsbach JM. The immediately failed lumbar disc surgery: incidence, aetiologies, imaging and management. Neurosurg Rev. 2014 Sep 23. [Epub ahead of print]

Dolatowski K, Malinova V, Frölich AM, Schramm R, Haberland U, Klotz E, Mielke D, Knauth M, Schramm P. Volume perfusion CT (VPCT) for the differential diagnosis of patients with suspected cerebral vasospasm: Qualitative and quantitative analysis of 3D parameter maps. Eur J Radiol 83; 1881-9, 2014.

Mielke D, Malinova V, Rohde V. Comparison of Intraoperative Microscopic and Endoscopic ICG Angiography in Aneurysm Surgery. Neurosurgery Suppl 3; 418-25, 2014.

Malinova V, Stockhammer F, Atangana EN, Mielke D, Rohde V. Catheter placement for lysis of spontaneous intracerebral hematomas: is a navigated stylet better than pointer-guided frameless stereotaxy for intrahematomal catheter positioning? Transl Stroke Res 5; 407-14, 2014.

Mielke D, Mayfrank L, Psychogios MN, Rohde V. The anterior interhemispheric approach - a safe and effective approach to anterior skull base lesions. Acta Neurochir (Wien) 156; 689-96, 2014.

Behm T, Horowski A, Schneider S, Bock HC, Mielke D, Rohde V, Stockhammer F: Concomitant and adjuvant temozolomide of newly diagnosed glioblastoma in elderly patients. Clin Neurol Neurosurg 115; 2142-2146, 2013

Mielke D, Wrede A, Schulz-Schaeffer W, Taghizadeh-Waghefi A, Nitsche MA, Rohde V, Liebetanz D: Cathodal transcranial direct current stimulation induces regional, long-lasting reductions of cortical blood flow in rats. Neurol Res 35; 1029-37, 2013

Psychogios MN, Scholz B, Rohkohl C, Kyriakou Y, Mohr A, Schramm P, Wachter D, Wasser K, Knauth M. Impact of a new metal artefact reduction algorithm in the noninvasive follow-up of intracranial clips, coils, and stents with flat-panel angiographic CTA: initial results.. 2013 Apr 16. [Epub ahead of print]

Wachter D, Behm T, von Eckardstein K, Rohde V. Indocyanine Green Angiography in Endoscopic Third Ventriculostomy. Neurosurgery 2013 Jan 10. [Epub ahead of print]

Wachter D, Reineke K, Behm T, Rohde V. Cranioplasty after decompressive hemicraniectomy: Underestimated surgery-associated complications? Clin Neurol Neurosurg 2012 Dec 26. [Epub ahead of print]

Wachter D, Kallenberg K, Wrede A, Schulz-Schaeffer W, Behm T, Rohde V. Fluorescence-guided operation in recurrent glioblastoma multiforme treated with bevacizumab-fluorescence of the noncontrast enhancing tumor tissue? J Neurol Surg A Cent Eur Neurosurg 73; 401-6, 2012.

Wachter D, Psychogios M, Gilsbach JM, Rohde V: Spinal cord cavernoma-operative strategy and results in 30 patients.J Neurol Surg A Cent Eur Neurosurg. 2012 May;73(3):125-31

Rohde V, Behm T, Ludwig H, Wachter D: The role of neuronavigation in intracranial endoscopic procedures. Neurosurg Rev 35; 351-8, 2012

Wachter D, Psychogios MN. [Carotid artery agenesis: anatomic normal variant or a risk for the patient?]. Rofo. 184; 65-7, 2012

Wachter D, Christophis P, Stein M, Oertel MF. Use of multimodal electrophysiological monitoring to predict outcome after subarachnoid hemorrhage? - A prospective series. J Neurosurg Sci 55:179-187, 2011.

Psychogios MN, Wachter D, Mohr A, Schramm P, Frölich AM, Jung K, Rohde V, Knauth M: Feasibility of flat panel angiographic CT after intravenous contrast agent application in the postoperative evaluation of patients with clipped aneurysms. AJNR Am J Neuroradiol. 2011 32; 1956-62, 2011

Wachter D, Hans F, Kreitschmann-Andermahr I, Rohde V. Lower incidence of transcranial Doppler and symptomatic vasospasm after aneurysmal subarachnoid hemorrhage and aneurysm clipping in the elderly patient? Neurosurgery 69:261-266, 2011;

Wachter D, Gondermann N, Oertel MF, Nestler U, Rohde V, Böker DK. Pituitary insufficiency after operation of supratentorial intra- and extraaxial tumors outside of the sellar-parasellar region? Neurosurg Rev 34:509-516, 2011.

Wachter D, Kreitschmann-Andermahr I, Gilsbach JM, Rohde V. Early surgery of multiple versus singular aneurysms after subarachnoid hemorrhage - An increased risk for cerebral vasospasm? J Neurosurg 114:935-941, 2011

Rohde V, Wachter D.Editorial Response: Early surgery of multiple versus singular aneurysms after subarachnoid hemorrhage - An increased risk for cerebral vasospasm? J Neurosurg 114, 2011

Wachter D, Wrede A, Schulz-Schaeffer W, Taghizadeh-Waghefi A, Nitsche MA, Kutschenko A, Rohde V, Liebetanz D: Transcranial direct current stimulation (tDCS) induces changes of cerebral perfusion (CBF) in an experimental rat model. Exp Neurol 227:322-327, 2011

Wachter D, Hans F, Psychogios MN, Knauth M, Rohde V: Microsurgery can cure most intracranial dural arterio-venous fistulae of the sinus and non-sinus-type. Neurosurg Rev. 34:337-345, 2011

Wachter D, Behm T, Gilsbach JM, Rohde V. Neurosurgical strategies and operative results in the treatment of tumors of or extending to the petrous apex. Minim Invasive Neurosurg 54:55-60, 2011

Dengler J, Heuschmann PU, Endres M, Meyer B, Rohde V, Rufenacht DA, Vajkoczy P: Giant Intracranial Aneurysm Study Group. The rationale and design of the Giant Intracranial Aneurysm Registry: a retrospective and prospective study. Int J Stroke 6:266-270, 2011

Wachter D, Böker DK, Huegens-Penzel M, Kuchelmeister K, Jödicke A. First manifestation of lambda positive plasmacytoma in the orbital apex with acute unilateral loss of vision - case report and review of the literature. Minim Invasive Neurosurg 53:74-76, 2010

Wachter D, Psychogios M, Knauth M, Rohde V. ivACT after aneurysm clipping as an alternative to digital subtraction angiography - first experiences. Cen Eur Neurosurg 71:121-125, 2010

Wachter D, Brückel A, Stein M, Oertel MF, Böker DK, Christophis P. 2-Octyl-cyanoacrylate for wound closure in cervical and lumbar spinal surgery. Neurosurg Rev 33:483-489, 2010

Wachter D, Gündling K, Oertel MF, Stracke H, Böker DK. Pituitary insufficiency after traumatic brain injury. J Clin Neurosci 16:202-208, 2009

Wachter D, Tschischka S, Huegens-Penzel M, Kuchelmeister K, Bohle RM, Böker DK, Nestler U. T-cell-lymphoma mimicking schwannoma of a cervical nerve root. Neurosurg Rev 32:117-121, 2009

Oertel MF, Scharbrodt W, Wachter D, Stein M, Schmidinger A, Böker DK. - Arteriovenous differences of oxygen and transcranial Doppler sonography in the - management of aneurysmatic subarachnoid hemorrhage. J Clin Neurosci 15:630-636, 2008

Picht T, Wachter D, Mularski S, Kuehn B, Brock M, Kombos T, Suess O. Functional magnetic resonance imaging and cortical mapping in motor cortex tumor surgery: complementary methods. Zentralbl Neurochir 69:1-6, 2008

Oertel MF, Schwedler M, Stein M, Wachter D, Scharbrodt W, Schmidinger A, Böker DK. Cerebral energy failure after subarachnoid hemorrhage: the role of relative hyperglycolysis. J Clin Neurosci 14:948-954, 2007

Oertel MF, Kästner S, Scharbrodt, Stein M, Mielke D, Böker DK. Chronischer Hydrocephalus nach aneurysmatischer Subarachnoidalblutung im Zeitalter von German Diagnose Related Groups (G-DRG). Gesundh Ökon Qual Manag 11: 221- 225, 2006

 

Neurochirurgie Göttingen

Die Neurochirurgische Klinik der Universitätsmedizin ist mit 5.000 ambulanten und 2.000 stationären Patienten sowie 3.000 Operationen pro Jahr eine der größten neurochirurgischen Kliniken Deutschlands.

Kontakt

Universitätsklinikum Göttingen
Neurochirurgische Klinik
Robert-Koch-Strasse 40
37075 Göttingen

Tel. 0551 39-66033

Fax 0551 39-8794

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